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Chapter 438(1/2)

The New Year is almost here...

After Lu Cheng cleaned up the house, he was not idle. He first followed Fang Nixin's suggestion and read the literature related to thyroid, breast and Ewing's sarcoma.

Now that I have decided to take advantage of the relatively abundant time now to conduct basic experiments, I have to start.

Lu Cheng just scanned the more classic articles and found that in the field of Ewing's sarcoma, there is currently only one targeted drug for Ewing's sarcoma, and it only targets distant metastasis staging, that is, before the terminal stage.

patients have better outcomes.

And it is not effective for all patients. Although the monoclonal antibody drug was made by Lu Cheng's master Lin Hui, it still has no specific effect on some patients.

Looking back at the field of breast cancer, Lu Cheng himself saw only three or four types of specific targeted drugs.

At present, breast cancer is one of the few tumors that has standardized surgical diagnosis and treatment in the field of tumor diagnosis and treatment.

The depth of research on orthopedic-related tumors is far behind that of breast tumors.

Of course, the research results on breast tumors can only be used as a reference for orthopedic-related tumors, but not for promotion. Otherwise, someone would have already tried breast cancer drugs in the field of orthopedic tumors.

The cells and glands in each part of our body, as well as their own environment and functions, are different. Therefore, the clinical manifestations and pathological mechanisms after illness are also very different.

There is a long way to go.

However, no matter what, at least on the road ahead, with Lin Hui as the pathbreaker, at least I know how to learn new topics in orthopedics and Ewing's sarcoma. If I can't get it so in-depth, I won't care about it for now.

Let’s talk after we get out the door.

The most talked about tumor is staging.

However, after Lu Cheng carefully reviewed the relevant information and literature, he discovered that other orthopedic tumors have staging, and Ennecking staging is often used. Even giant cell tumors of bone have their own unique staging.

However, Ewing's sarcoma does not have its own unique staging system.

The research is still not thorough enough.

Lu Cheng doesn't understand it himself, but he can ask his master Lin Hui for help.

After making a phone call and chatting for more than two hours, Lin Hui learned almost everything he could.

But Lu Cheng did not get an accurate answer. It was similar to Ennecking in stages, and Lin Hui also gave a certain amount of guidance on the corresponding steps and plans. However, because Lin Hui had not delved deeply into this field for a long time, he gave

Without a specific plan, Lu Cheng and Fang Nixin could only find it themselves.

At present, the Ennecking staging of bone tumors consists of GTM. G is the pathological grade: G0 is benign, G1 is low malignant, and G2 is high malignant. T is the anatomical location of the tumor: T0 is benign tumor limited to the bone, T1 is intracompartmental,

Outside room T2. M refers to transfer: M0 has no transfer, M1 has transfer.

Lu Chengcheng first went to the Second Orthopedics Ward and found the director of the Second Orthopedics Ward, Director Liu Jun.

After explaining his intention, Liu Jun welcomed him very much.

Although he is the director of the bone tumor department and has excellent academic performance, he is still far behind Lu Cheng's teacher, Lin Hui, so after learning that Lu Cheng wanted to delve deeper into Ewing's sarcoma

time.

He was very cooperative and said that if Lu Cheng needed any help, he could provide manpower and laboratory support.

Well, Liu Jun is good at academics, and the hospital has its own dedicated laboratory.

Moreover, Liu Jun also exchanged some experiences and ideas with Lu Cheng in the field of bone tumor research, and also told Lu Cheng that if the Department of Orthopedics at the current Second Xiangya Hospital is to be selected for the next national key discipline construction project,

The only difference is in the academic field.

In orthopedics now, the most vacant and blank academic field is bone tumors, so I hope Lu Cheng can do a good job and work together to make up for the weaknesses in the research field.

He is studying osteosarcoma. Although it is not the same type of tumor as Ewing's sarcoma, they are both derived from the stroma. During the experiment, many experimental reagents are common. Lu Cheng can work with Fang Ni if necessary.

Xin went to his laboratory and used it by herself without Lu Cheng's subsidy.

Moreover, after having in-depth contact with Director Liu Jun for a long time, Liu Jun also said something that touched Lu Cheng quite a bit.

That is, in the Second Xiangya Hospital, although there are many research groups in the Department of Orthopedics, for example, Qu Hongsheng is also studying bone tumors, and people from the spine surgery department are also studying bone tumors, but in fact, these research groups are completely focused on

Articles and topics.

I don’t have any special ideas about the construction of disciplines and academics.

Before Liu Jun, he could not stay. Even with a large number of articles as support, it was difficult to stay. The former director of the Department of Orthopedics, Liu Jun’s mentor, slapped the table in front of the hospital leaders. He

That's why he stayed.

Now after so many years, he still has not made any substantial academic achievements. First, he has not really chaired a project for a long time, and second, he cannot find like-minded people.

After knowing that Lin Hui was an academic master in the past, he visited Lin Hui, but Lin Hui could not overcome his inner obstacles and was unwilling to cooperate. He felt quite regretful...

Liu Jun also gave Lu Cheng a relatively large amount of information, including some clinical information on current and past patients in the department that Liu Jun himself had collected.

This surprised Lu Cheng.

After Liu Jun left, Lu Cheng reflected and realized how lucky he was to be able to stay in the hospital.

All of this is because I went to the capital city and accidentally made a big move in the world-class field of vascular surgery. Then some large hospitals in the capital and Kyoto robbed people. Otherwise,

It is almost impossible for Lu Cheng to stay.

The Second Xiangya Hospital, from the perspective of Changshi First People's Hospital, is a third-level comprehensive hospital with a good academic atmosphere and strong professionalism.

However, if we look at it from the perspective of the No. 9 Hospital in Shanghai, in fact, the Orthopedics Department of the Second Xiangya Hospital is indeed extremely professional, but it has reached a very subtle critical point. If it had not taken such an innovative step, it would not be possible now.

The status of the Orthopedics Department of the Second Xiangya Hospital needs to be lowered.

The current clinical level of the Second Xiangya Hospital is among the top in the conventional field, but these surgeries are actually being gradually carried out in prefecture-level municipal hospitals. If you still don’t want to be in line with the world’s first-class standards, then you are regressing!

Liu Jun really wanted to throw away the brand name of Second Xiangya Hospital in the field of orthopedic diseases.

Liu Jun also said that although he was the only one invited to the conference organized by the International Orthopedic Association of the Second Xiangya Hospital, in fact, the lectures he gave there were still not innovative enough and were still a bit cliché. Some people even watched his lectures.

From the beginning, you can guess the ending.

Of course, Liu Jun also felt that Lu Cheng's appearance might affect some of the hospital's subsequent decisions...

Lu Cheng thought for a long time and decided not to think about this relatively sensitive topic.

In this world, no position is reserved for the top people, it is only reserved for the most suitable people.

Lu Cheng first collected the basic information of the patients in the hospital and the patients with Ewing's sarcoma who had been hospitalized in the past month, and then checked them one by one. Unfortunately, through reviewing the medical records, Lu Cheng found that some patients' examination information was obtained from subordinates.

If it is brought by the hospital, it may not be queried through the hospital’s system.

Among all the current patients, only three have Ewing's sarcoma, and they are neither too old nor too young.

Lu Cheng saw these three patients. Because Lu Cheng was wearing a white coat, the family members of the three patients cooperated to show Lu Cheng all the examination results and also allowed Lu Cheng to take photos.

Just when he walked out of the last boy's ward, the little boy said something.

"Mom and Dad, this big brother is so tall. Will I ever be able to grow so tall?"

Then Lu Cheng heard his parents crying.

Lu Cheng closed the door quietly. He knew the answer himself. It was almost impossible.

From the moment he received medical treatment, this child has been determined to be in the metastatic stage of Ewing's sarcoma. Even the best targeted drugs currently available are of no use for tumors of this level...

But the fate of a poor and cute child was not something Lu Cheng could control or reverse.

He originally had a battle scene system that could make him happy for a lifetime, but that artifact has been given to another equally cute little girl, Chu Yiyi...

The onset period of bone tumors is in teenagers and children in the period of rapid growth.

Like leukemia, it only causes trouble for children.

After Lu Cheng calmed down, he went back to chasing the data of patients who had been discharged. He hoped that the radiology department's radiography reading system would be able to contain all the data from the moment of admission to the outpatient department.

Three days later, Lu Cheng obtained the admission conditions for the radiology department through the intervention and adjustment of the hospital's medical department.

I got my own account and password.

Some colleagues in the radiology department had no idea that a stranger from the orthopedics department was about to arrive in the radiology department, because this kind of thing only requires the approval of the director.

So when Lu Cheng wore a white coat and went to the radiology clinic's reading area, he logged in with his own account and password.

There is no obstacle at all, except that some people will occasionally glance at Lu Cheng and regard him as a regular trainee or a rotating graduate student, forget it.

After Lu Cheng settled down, he went through the film reading system, one by one, calling up the films taken during the patient's outpatient clinic and the films taken after admission. He browsed them all, and then almost confirmed the diagnosis, or saw very typical symptoms.

Mark the film with a pen.

I also took photos with my mobile phone.

These pictures are the best original materials for writing articles.

This method was taught to him by Fang Nixin. It is a practical and stupid method.

Moreover, for general tumor staging, the prognosis is completely different before metastasis and before metastasis.

Although pulmonary metastasis of Ewing sarcoma is relatively rare, it is not that rare. Because the average patient has no symptoms before, and when symptoms develop, when they come to see a doctor, there are already brothers of Ewing sarcoma in the lungs.

And it’s even found all over the body.

Therefore, Lu Chengcheng also planned to take a chest X-ray to see if he could find nodules.

Oops, the ground glass shadow in the interstitium of the lungs is so classic. I have a cold.

This kind of ground glass opacity is actually protein filling the interstitium of the lungs, which is a manifestation of pneumonia. Unfortunately, I am not a teacher of respiratory medicine. Otherwise, this would definitely be a particularly good way to teach students about pneumonia.
To be continued...
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