Chapter 471 Are you the only one who is generous?

"The optimal treatment process based on the current patient database statistics?" Huang Jing was a little confused.

Lu Cheng is currently responsible for basic research, but just now, Lu Cheng's description was clearly about clinical aspects.

Lu Cheng has basically never been to a clinical clinic, so how could he bring up such a thing? Could it be that Lu Cheng secretly went to a clinical clinic?

It's not that it was a mistake for Lu Cheng to go to the clinic. His job is to be a doctor, and treating diseases and saving people is what he should do. It's just that now he can do more things and save more people. As a doctor, you don't necessarily have to rely on

Only by treating the disease can the disease be cured.

If Lu Cheng could develop anti-VI drugs as soon as possible, it would be truly a blessing.

"Yes, Director Huang, you also know that our research group has newly added Fang Nixin, and there is also Dong Zhen, who is quite talented in mathematics and computer fields. He is now my graduate student."

"So after I obtained the patient database information, I used crawler software to crawl all the patient information, and then analyzed the results."

"This idea was thought of by Fang Nixin of our research group when he was ill." Lu Cheng wanted to avoid unnecessary misunderstandings, so he gave the credit to Fang Nixin and Dong Zhen!

For him now, more honors and less similar honors are really nothing.

As long as Lu Cheng can take this plan seriously as soon as possible, that's the right thing to do.

"Okay, I understand. I will submit this plan to the expert group for review tomorrow."

Huang Jing agreed, and then said: "But Lu Cheng, what everyone hopes for you now is basic scientific research, and we also know that the focus of your work is there."

"And there are many reasons why there is no unified clinical treatment plan so far."

"Because each professor has his own understanding of specific diseases and symptoms, there will be certain differences in treatment plans. Standardization is actually quite difficult to implement."

"Besides, your current data are only of statistical significance and may not attract too much attention."

After Lu Cheng listened, he pondered for a while and then said: "It doesn't matter, Director Huang. I called mainly because I felt it was necessary to tell you that I have done this, not to ask you to promote this plan or anything else."

"But Director Huang, it doesn't matter if other experts or professors don't trust this plan, but I hope to make it public and use it as a reference. Do you think it's okay?"

Whether others believe it or not is their business.

real.

If an internal medicine doctor came and said that he had created a new orthopedic surgery that needed to be promoted, Lu Cheng's first reaction would be disbelief.

Scientific research and clinical practice are two quite different directions. Of course, a graduate student in orthopedics can do experiments and research on respiratory medicine. As long as he masters the basic skills and has some unique understanding abilities, he can definitely do it.

But it does sound a bit nonsense for an orthopedic doctor to interfere with other people's respiratory medicine diagnosis and treatment plans.

However, Lu Cheng didn't want to convince Huang Jing, he just wanted to take it out as soon as possible. It would be best if someone believed in it. Even if he doesn't believe it now, as time goes by, it will definitely leave a subconscious feeling, and then slowly move forward.

Lu Cheng couldn't guarantee that the plan he gave was really the most optimal one. He just went through tens of thousands of simulations and finally got such an optimal plan. And in reality, during the statistical process, it was also

Very close to this plan.

Therefore, even if this solution is not the optimal solution, it is certainly one of the best solutions that can be thought of so far.

The significance and charm of statistics lies in obtaining general rules through sample simulation.

The more times the simulation is performed, the closer it is to the truth. This is called sample-to-generalization.

"Well, okay!"

"Xiao Lu, please take the trouble. Go to bed early, it's not too early now."

"While you are working, you must also pay attention to your body. Now that you are responsible for the general direction of the entire experimental process, you cannot fall down."

"By the way, when you review the experimental progress of the existing research group, you must strictly follow the principles. Once someone violates the rules or there are ethical issues, you must stop the research as soon as possible!"

"Our country in China will never allow scientific research on the behavior of lunatics." Huang Jing ordered seriously.

At this special time point, Huang Jing is really afraid that some research groups will take the wrong approach and do some research across the timeline.

For example, we can directly take drugs and test them directly on humans, bypassing animal experiments, and get results as quickly as possible.

The sooner you are right, the sooner you become famous; the sooner you are wrong, the sooner you correct it.

This kind of thing happened just a few days ago. In order to speed up its pace, some research groups seemed to have vaccinated some vaccines on living subjects on a small scale.

Someone who understands the rules of the hospital reported it, and now the two leaders of the entire research team are under control.

The ignorant and enthusiastic people who are willing to contribute to the fight against VI got in touch as soon as possible and are observing its side effects 24 hours a day!

This is a taboo.

There is no experimental protocol that can bypass animal experiments and go directly to humans.

This is true whether it is domestic or foreign.

This is also a very important value of the Ethics Society today. Every topic must be recognized, and the certification report of the Ethics Society is the top priority.

If ethical issues arise in the topic, the Ethics Society will be jointly and severally responsible.

If there is no certification report, all research progress and results will be invalid.

This is a bloody lesson bought with life in the early stages of the development of medical experiments in the long history of history.

…

Lu Cheng nodded and said: "Director Huang, I carefully read the daily progress report, and the deputy team leaders will also review it again."

"It's just Director Huang, I thought of a problem, that is, if some research groups are lying about their progress, then I have no way to monitor their experimental procedures, whether they comply with regulations, and whether there are any violations."

"So I suggest that research units that are currently conducting similar projects should strictly set up a monitoring team, and people from the ethics society and scientific research department of the unit will be responsible for monitoring. They will not interfere with the experimental progress and steps, only monitor

Whether the experiment complies with the process."

"This is very necessary."

Lu Cheng heard Lin Hui mention this matter. He must pay attention to the experimental process! Pay attention to supervision. He also heard Lin Hui say this kind of thing.

"Okay! You are a knowledgeable person in this regard. I listen to you. I will issue the document in the name of the office and let all units coordinate and deploy." Huang Jing also felt that supervision cannot be a matter of one person, nor can it be done by one person.

It's just a one-sided matter.

However, in order to speed up the progress of the experiment, you must not advance the experimental process in an illegal or over-the-top manner.

…

The next day, Lu Cheng came to the laboratory early. After walking around Dong Zhen and others' laboratories, and then reviewing the experimental progress of their respective groups, he started busy work, started reading emails, and

Various materials, and then provide answers to questions raised by some research groups.

In addition, we also need to conduct academic exchanges with people from other sub-direction research groups on the VI research topic and exchange opinions with each other.

In addition, what Lu Cheng still has to do is video conferencing, video conferencing, and video conferencing.

About one o'clock in the afternoon.

Fang Nixin called and told Lu Cheng the good news: "Lu Cheng, I have convinced the director of the Department of Critical Care Medicine and Respiratory Medicine of our hospital. They agreed with our treatment concept based on the data analysis we provided.

"

"This morning, two teachers invited me to a video conference. I analyzed in detail the theoretical reference of this plan and the ideas we analyzed after sorting it out."

"They feel they can conduct therapeutic experiments in small quantities and in batches."

"Because the corresponding drugs already have sufficient clinical data support, the protocol is just slightly adjusted and more standardized. Therefore, there is no need to go through other additional procedures."

"It is estimated that such treatment will be able to start from this afternoon. And they have also given suggestions for randomization of RCT."

"In addition to dividing the experimental group and the control group, the experimental group and the control group respectively select patients with different degrees of severity as subgroups. In addition to within-group analysis, a subgroup analysis can also be done."

"At the same time, we can also make a comprehensive comparison between the patients in the experimental group and the patients in all databases across the country!"

"I'm really looking forward to the promotion effect of this plan."

Fang Nixin is a person who understands research, so she speaks very professionally.

The traditional randomized controlled trial, also known as RCT, is different from the retrospective controlled study RCS! It adopts a double-blind method to minimize unnecessary errors.

Setting up subgroup analysis within the experimental group and the control group is more scientific, requires greater workload, and requires a more rigorous attitude in data analysis.

The professors in the Department of Respiratory Medicine are also impatient.

Of course, Lu Cheng knew that the respiratory department of the Second Xiangya Hospital was really strong in terms of hard power and was definitely among the top seven in the country. The specific ranking was not clear, but it had not fallen out of this level for a long time.

Not only are they clinically powerful, but they are also very in-depth in scientific research. Whether it is basic research or clinical research, they have been carried out quite extensively and in depth.

"The teachers have worked so hard. I believe the final result will be very good," Lu Cheng replied.

As expected, family members are easier to talk to and willing to help you.

Lu Cheng only mentioned the previous training plan to Nie Yayun, and Nie Yayun actually implemented it and promoted it. Today's standardized treatment plan is still the same.

There is a saying that goes well, if you look at the entire department, everyone in each department is united.

Looking at the entire Shashi, Xiangya Hospital and the Second Xiangya Hospital are two separate hospitals, competing against each other.

As long as you go out of the province, the three hospitals in the Xiangya system are like three brothers who broke bones and connected tendons.

"Well, I hope so too."

"Also. I have already made the breakpoint regression design plan. You said it would be better for me to find someone to write the code. Or should you find someone to write it?" Fang Nixin knew that Dong Zhen could write code.

.
To be continued...